Vol. 7, Issue 1, Part B (2025)

The Complete Blood Count (CBC) is a vital diagnostic tool used in clinical laboratories to assess a patient’s overall health and detect various disorders, including anemia, infection, and leukemia. The accuracy and reliability of CBC results hinge on the proper maintenance and calibration of analyzers utilized in these tests. This paper provides an extensive review of the principles of operation of CBC analyzers, the maintenance protocols necessary to ensure their optimal performance, and the calibration processes required for valid test outcomes
Complete blood count analyzers (CBC) serve as fundamental instruments in clinical laboratories, playing a key role in assessing patient health. A CBC is a comprehensive test that evaluates various blood components, including red blood cells, white blood cells, hemoglobin, hematocrit and platelets. These parameters are essential for the diagnosis of a number of conditions, from anemia and infections to hematological disorders. The objective of CBC analyzers, therefore, extends beyond mere data collection; They facilitate doctors in informed decisions on the patient's management and treatment routes. Given its extensive use and meaning in the diagnosis of patients, the precision of the performance of these analyzers is critical.