Vol. 6, Issue 2, Part B (2024)

Chronic Suppurative Otitis Media (CSOM) is a persistent inflammatory disease of the middle ear and mastoid cavity, marked by recurrent or continuous discharge through a perforated tympanic membrane. It is a major global health concern, particularly in low- and middle-income countries, where limited access to healthcare exacerbates its prevalence and impact. The condition is associated with significant morbidity, including hearing loss and potential life-threatening complications. This review explores the multifaceted aspects of CSOM, encompassing its epidemiology, etiology, pathophysiology, clinical presentation, diagnostic methodologies, and therapeutic interventions. Moreover, the paper highlights recent advancements in biofilm management, regenerative therapies, and the role of vaccination in disease prevention. Emphasizing a comprehensive understanding of CSOM is crucial for developing effective management strategies and mitigating its socioeconomic burden.