Vol. 6, Issue 2, Part A (2024)

Influenza remains a persistent global threat, with pandemic potential posing substantial health risks. Ongoing global surveillance of emerging influenza strains is crucial to pre-empting future crises. This exploration emphasizes the necessity for preparedness, focusing on surveillance, vaccine development, and international collaboration to mitigate influenza transmission. While vaccination is pivotal in pandemic control, ensuring rapid vaccine availability during outbreaks remains challenging. Advances in novel vaccine technologies offer promising solutions for scalable production under pandemic conditions. This review consolidates influenza's historical impact and ongoing evolution, presenting complex challenges from seasonal epidemics to potential pandemic outbreaks. Vigilant surveillance of evolving strains, including avian influenza variants like H5N1, H7, and H9, is essential for effective preparedness. The World Health Organization plays a central role in coordinating global influenza surveillance, guiding vaccine strategies, and facilitating rapid response efforts worldwide. Collaborative efforts across national and international health sectors are critical to enhancing global readiness against influenza pandemics through proactive vaccine development, surveillance capabilities, and robust public health preparedness initiatives.